Hitting the tourist sites and seeing the best of the city in only three days and three nights.
Step 1
Arrive early in the city on the first morning by plane, bus, etc.
Step 2
Hit the historic Roman landmarks: the Colosseum, the Roman Forum, the Pantheon, and the Circus Maximus.
One of the most historic landmark of Rome is the Colosseum (70–80 AD), the largest amphitheater ever built in the Roman Empire.It reflects the architectural beauty of Roman engineering. 
The oldest and most important structure-The Roman Forum is located between the Palatine hill and the Capitoline hill of the city of Rome. Roman Forum is also referred as the "Forum Magnum" or just the "Forum". 
The Pantheon -one of the oldest standing domed structure in Rome was built as a temple to all the gods of Ancient Rome.It was believed to be built in the 126 AD.
Step 3
Spend the first evening at a local restaurant and then go to the Spanish Steps for night life.
Step 4
Spend the entire second day at Vatican City. Go to the top of the dome; see the crypts, monuments, painting, and statues along the way. You can even decide to visit the Vatican Museums: the ticket costs about 14 €. It is worth to see if you are fond of Arts. The only bad thing is that the line could be very long and it would take you hours to get in it. If you are interested in visiting the Museums, go there early in the morning (around 0700-0730) to avoid long waitings.
Step 5
Spend the second night at the Trevi Fountain. Enjoy dinner at a local cafe.
Step 6
The third day is for catching up. Walk to the historic places you missed, and do some shopping for the special lady/guy in your life.
Step 7
Have a special farewell dinner before you leave the "Eternal City".
Tips
- You will see the letters "SPQR" a lot when you are there. SPQR stands for "Senatus Populusque Romanus", or "The Senate and the People of Rome". This was one of the seals of Rome.
- A whole day is needed for the Vatican. Dress properly in order to have the opportunity to access it. Men's legs need to be completely covered (trousers only). Ladies can wear knee length skirts/shorts. Both men & women are to have shoulders covered. Children are excluded from these regulations.
- Skip the morning line at the Vatican Museums by going to St. Peter's Basilica in the morning, visiting the Vatican after lunch. There will be almost no line at 1pm. The Sistine Chapel is inside the Vatican Museums.
- Buy tickets for the Coliseum at the Palatine Hill. You'll skip the queue at the Coliseum and the tickets are valid for both.
- Be sure to get inside the Coliseum. Some guides will just walk around the outside.
- Brush up on the basics of the Italian language.
- Although you have to pay for the Coliseum, Vatican Museums and some other attractions, most of Rome's monuments are free. These include the Pantheon, Spanish Steps, Trevi Fountain, Piazza Navona, Campo Di Fiori, the Roman Forum, and St. Peter's.
- If you want to save money and you feel too lazy to walk around the city, use the metro to move. There are 2 lines, A and B, by which you can reach almost every corner of the city. The ticket costs 1 € per ride.
- Research the city thoroughly before you go - that way, you can make sure you see all the things you want to. A few good websites are Wanted in Rome, Rome File, the wikitravel page on Rome and the official site of tourism in Rome Romaturismo . In this site, there are even some good itineraries for people who don't have much tome to spend in Rome.
Warnings
- Watch for pick-pockets, especially on underground Metro stops and around touristy areas and monuments. Most travellers use a money belt which you wear inside your pants.
- Only use official taxi cabs.
- If you want to take a ride in one of the horse-drawn carriages, make sure you've agreed a price before you set off.
Things You'll Need
- Pocket phrase book.
- Euros (many)
- Map (get a miniature one for easy consulting in a busy street)
- Guidebook
